2-FDCK (also known as 2-Fluorodeschloroketamine, 2F-Ketamine or 2-Fl-2′-Oxo-PCM) is a novel dissociative substance of the aryl cyclohexylamine class that produces dissociative, anesthetic, and hallucinogenic effects when administered to humans. It is structurally related to other chemicals like ketamine and deschloroketamine (DCK) and is reported to produce similar effects.

This is a drug that is chemically similar to ketamine and is sometimes incorrectly marketed as such. Since it’s rise is popularity 2fdck has been used as a cheaper ketamine alternative… We’ll go over the history, dangers, and side effects, pharmacology and everything in between.

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2-Flurodeschloroketamine or 2-fdck is a lesser known dissociative substance of aerocyclohexamine class just like ketamine, PCP and MXE. It is thought to act as an nmda recpetor. Although research is currently limited to 2-fdck’s effects are reported to be very similar to ketamine.

It is an analog of ketamine where the chlorine group has been replaced by flourine. Both drugs effects are highly dose dependent with lower doses of producing alcohol-like ntoxication and higher doses producing hallucinogen out-of-body state AKA the “K-hole”. The origins of 2fdck are not really well documented.

The synthesis of 2fdck was first described in a 2013 paper as a part of a larger effort to synthesize and evaluate new anesthetic drug based on ketamine and it’s analog subjective effects include; sedation, motor control loss, pain relief, internal hallucinations, conceptual thinking, euphoria and dissociation.

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The effects tend to last longer than normal ketamine and is claimed to be a bit more psychedelic as well as a light dose around 20 – 50mg. While a more common dose is 50 – 100mg. A strong dose is deemed at 100 – 175mg and more. Once injested, takes 20 – 40 mins and the duration effects lasts about 1 – 2 hours.

2fdck works better via oral administration than ketamine which can be a real benefit to those who don’t do needles or have a destroyed sinus cavities like other dissociatives. 2FDCK is thought to close the nmda receptors by blocking them.

This disconnection of neurons leads to a loss of feelings, difficulty in moving and eventually leading to an ego death. Ego death is when the user feels like their thoughts are separated from their bis and their minds become a single point of consciousness that ca be eerily similar to the feeling of falling in an M-hole, which is the MXE equivalent of the K-hole.

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2-FDCK first came on the research chemical scene back in 2017, shortly after the release of DCK, as it was sold as a legal alternative to ketamine. It has since the most popular and highly sold RC dissociative on the market today. The effects of 2-FDCK are generally regarded as the closest to ketamine of any RC dissociatives.